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A new clinical guideline to manage cholesterol levels in the blood has been released by the American College of Cardiology. Johns Hopkins cardiologist Seth Martin participated in writing the guidelines and says that shifting risk assessment and management strategies for …

New cholesterol screening guidelines capture childhood risk, too, Elizabeth Tracey reports Read more »

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The good news is heart failure in people with severe obesity may be reversible with common weight loss drugs. The bad news is both obesity, with BMIs of around 30, and severe obesity, with a BMI of 42 or greater, …

Increasing rates of obesity and severe obesity may presage increased rates of heart failure, Elizabeth Tracey reports Read more »

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GLP-1 receptor agonists are effective in helping most people lose weight, and now a new study suggests that in those with severe obesity, a BMI of 42 or greater and who have a type of heart failure, this condition may …

Is there another benefit besides weight loss of GLP-1s in people with severe obesity? Elizabeth Tracey reports Read more »

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There’s a relationship between severe obesity and one type of heart failure, and it looks like it’s mediated by adding more phosphate groups, a process known as phosphorylation, to proteins in heart muscle cells, specifically to units within the muscle …

Can GLP-1 agonists help in heart failure and severe obesity? Elizabeth Tracey reports Read more »

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Severe obesity may impede the ability of units inside heart muscle cells called sarcomeres to contract, and losing weight may reverse that condition. That’s according to research by cardiologist David Kass and colleagues at Johns Hopkins, who looked closely at …

What is severe obesity doing to the heart muscle’s ability to contract? Elizabeth Tracey reports Read more »

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Heart failure with preserved ejection fraction, so-called HFpEF, is happening more frequently, especially in those with severe obesity. David Kass, a cardiologist and researcher at Johns Hopkins, and colleagues, have looked closely at heart muscle cells from this group of …

How is obesity related to a common form of heart failure? Elizabeth Tracey reports Read more »

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A large number of people who could benefit from medicines to reduce cholesterol and consequent cardiovascular risk aren’t taking them, a study by Caleb Alexander, a drug efficacy expert at Johns Hopkins, and colleagues has shown. Alexander says this has …

Many people who could benefit from medicines to reduce their cardiovascular risk aren’t getting them, Elizabeth Tracey reports Read more »