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GLP-1 receptor agonists are effective in helping most people lose weight, and now a new study suggests that in those with severe obesity, a BMI of 42 or greater and who have a type of heart failure, this condition may …

Is there another benefit besides weight loss of GLP-1s in people with severe obesity? Elizabeth Tracey reports Read more »

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There’s a relationship between severe obesity and one type of heart failure, and it looks like it’s mediated by adding more phosphate groups, a process known as phosphorylation, to proteins in heart muscle cells, specifically to units within the muscle …

Can GLP-1 agonists help in heart failure and severe obesity? Elizabeth Tracey reports Read more »

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Severe obesity may impede the ability of units inside heart muscle cells called sarcomeres to contract, and losing weight may reverse that condition. That’s according to research by cardiologist David Kass and colleagues at Johns Hopkins, who looked closely at …

What is severe obesity doing to the heart muscle’s ability to contract? Elizabeth Tracey reports Read more »

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Heart failure with preserved ejection fraction, so-called HFpEF, is happening more frequently, especially in those with severe obesity. David Kass, a cardiologist and researcher at Johns Hopkins, and colleagues, have looked closely at heart muscle cells from this group of …

How is obesity related to a common form of heart failure? Elizabeth Tracey reports Read more »

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Would your loved ones know what to do if they had to make medical decisions on your behalf? For National Healthcare Decisions Day on April 16, Dr. Ivy Akid joins Medicine Made General to explain why planning ahead isn’t about …

Ep: 11 Decisions Your Loved Ones Shouldn’t Have to Guess | Medicine Made General Read more »

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A deep dive into leading through uncertainty, this episode explores practical tools for navigating change and transition, highlights listening as a critical leadership skill, and offers principles for authentic communication that every leader can use. Access the podcast here. Have an …

Ep 23: Leading Through Uncertainty: The Power of Listening in Times of Change | Johns Hopkins Medicine Office of Well-Being Read more »

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Brain organoids, collections of cells found in the brain, have been grown from blood samples of people with Alzheimer’s disease and used to assess the impact of a drug called escitalopram in a new study. Vasiliki Machairaki, study leader and …

A model of your brain may one day be grown in a lab, Elizabeth Tracey reports Read more »