Can an injectable particle help supercharge your T cells? Elizabeth Tracey reports

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CAR-T cells are a type of immune cell that have proven very effective for treating some types of cancer, yet limitations to their use exist. Biomedical engineering expert Jordan Green at Johns Hopkins says limitations including lengthy time and expense in having to produce CAR-Ts outside the body can be overcome by stimulating T cells with a particle he and his team have created.

Green: It's a polymer, it's a polyester. You might be familiar with some other polyesters used in medicine. For example if you've had biodegradable sutures, biodegradable stitches where those were put in but then over time they dissolved and so they didn’t have to be taken out again, this is very similar except it's designed to degrade even more quickly. What would be personalized is potentially the type of cargo that's inside of the particle. It could be a type of cargo that can work broadly across a lot of people with the same disorder or it could be a type of cargo that's more personalized for one specific for example cancer.  :34

At Johns Hopkins, I’m Elizabeth Tracey.