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Severe obesity may impede the ability of units inside heart muscle cells called sarcomeres to contract, and losing weight may reverse that condition. That’s according to research by cardiologist David Kass and colleagues at Johns Hopkins, who looked closely at …
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Heart failure with preserved ejection fraction, so-called HFpEF, is happening more frequently, especially in those with severe obesity. David Kass, a cardiologist and researcher at Johns Hopkins, and colleagues, have looked closely at heart muscle cells from this group of …
How is obesity related to a common form of heart failure? Elizabeth Tracey reports Read more »
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Brain organoids, collections of cells found in the brain, have been grown from blood samples of people with Alzheimer’s disease and used to assess the impact of a drug called escitalopram in a new study. Vasiliki Machairaki, study leader and …
A model of your brain may one day be grown in a lab, Elizabeth Tracey reports Read more »
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Extracellular vesicles are membrane bound packages cells use to jettison materials from inside the cell, a sort of trash can. Johns Hopkins genetic medicine expert Vasiliki Machairaki has shown in a new study that these vesicles may be a means …
What can be learned from what cells dispose of? Elizabeth Tracey reports Read more »
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What might a model of the hindbrain, which helps control functions like sleep, breathing and heart rate, tell us about using a common depression drug in people with Alzheimer’s disease? Genetic medicine expert Vasiliki Machairaki at Johns Hopkins says her …
Brain organoids can resemble specific parts of the brain, Elizabeth Tracey reports Read more »
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Drugs to manage symptoms of Alzheimer’s disease may work in some people but not in others. Now a new method using brain organoids, which are derived from a person’s own blood sample, may help determine whether a specific medication is …
Can drugs to manage Alzheimer’s disease be tested in organoids? Elizabeth Tracey reports Read more »
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Brain organoids are lab grown clusters of cells that have several of the cell types found in someone’s brain. Cells taken from a person’s blood are coaxed to become stem cells, then differentiate into brain cells. Vasiliki Machairaki, a genetic …
